Market Movers | Winners: PCRX, HAE, GFUZ | Losers: ANGO, PACB, GLAS
On Thursday, October 8, the S&P 500 fell 0.5%, the Nasdaq-100 dropped 1.4% and the Dow Jones Industrial Average inched up 0.1%. Over the past week the S&P 500 is up 1.3%, and over the past month it is up 1.7%.
Gainers outnumbered decliners 2,227 to 1,860 within the Trefis coverage universe. Pacira BioSciences (PCRX) gained 44.4% to lead the day, while AngioDynamics (ANGO) fell 20.9%, the weakest showing.

Thursday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the highest returns on Thursday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PCRX | Pacira BioSciences | 44.4% | 40.6% |
| 2 | HAE | Haemonetics | 17.5% | 49.1% |
| 3 | GFUZ | General Fusion | 14.6% | n/a |
| 4 | MANE | Veradermics | 14.1% | n/a |
| 5 | IPSC | Century Therapeutics | 14.1% | 46.8% |
| 6 | ACRS | Aclaris Therapeutics | 11.5% | 25.9% |
| 7 | SECZ | Securitize | 11.1% | n/a |
| 8 | COCO | Vita Coco | 10.5% | 5.6% |
| 9 | MAX | MediaAlpha | 10.4% | -17.5% |
| 10 | CATX | Perspective Therapeutics | 10.2% | -1.5% |
Thursday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the lowest returns on Thursday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ANGO | AngioDynamics | -20.9% | -12.5% |
| 2 | PACB | Pacific Biosciences of California | -15.4% | 23.0% |
| 3 | GLAS | Glass House Brands | -14.0% | n/a |
| 4 | AAOI | Applied Optoelectronics | -13.6% | 203.8% |
| 5 | MXL | MaxLinear | -12.7% | 437.6% |
| 6 | ORBS | Eightco | -12.2% | -47.2% |
| 7 | EQPT | EquipmentShare.com | -11.4% | n/a |
| 8 | HUT | Hut 8 | -10.9% | 73.2% |
| 9 | EOSE | Eos Energy Enterprises | -10.8% | -75.9% |
| 10 | AXTI | AXT | -10.2% | 338.3% |
For A Few Names, Thursday Extended A Monthly Trend
The 14.0% decline in Glass House Brands (GLAS) on Thursday was not a one-off: the stock is down 45.8% over the past month, and down 37.0% over the sessions before Thursday.
Securitize (SECZ) appears on both the one-day and one-month winners lists. It rose 11.1% on Thursday and is up 50.2% over the past month; excluding Thursday, it had already gained 35.2% over the other sessions.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PCRX | Pacira BioSciences | 45.5% | 40.6% |
| 2 | OPCH | Option Care Health | 37.5% | -2.5% |
| 3 | RXO | RXO | 35.4% | 128.9% |
| 4 | PTC | PTC | 32.3% | 11.2% |
| 5 | PENG | Penguin Solutions | 30.2% | 265.9% |
| 6 | LW | Lamb Weston | 20.1% | 21.0% |
| 7 | GFUZ | General Fusion | 19.8% | n/a |
| 8 | PRME | Prime Medicine | 19.7% | 3.2% |
| 9 | QDEL | QuidelOrtho | 19.6% | -56.5% |
| 10 | SOC | Sable Offshore | 17.3% | -57.2% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AVBP | ArriVent BioPharma | -42.2% | -16.9% |
| 2 | ANGO | AngioDynamics | -25.7% | -12.5% |
| 3 | EMAT | Evolution Metals & Technologies | -21.1% | n/a |
| 4 | ALMR | Alamar Biosciences | -20.2% | n/a |
| 5 | ORBS | Eightco | -19.2% | -47.2% |
| 6 | APMD | Apnimed | -19.2% | n/a |
| 7 | TWST | Twist Bioscience | -19.1% | 379.4% |
| 8 | STX | Seagate Technology | -18.1% | 182.3% |
| 9 | GLAS | Glass House Brands | -17.1% | n/a |
| 10 | ABSI | Absci | -16.8% | 156.2% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PACB | Pacific Biosciences of California | 78.3% | 23.0% |
| 2 | GRAL | GRAIL | 71.2% | n/a |
| 3 | DNA | Ginkgo Bioworks | 67.0% | 36.5% |
| 4 | IOVA | Iovance Biotherapeutics | 57.9% | 387.5% |
| 5 | BALY | Ballys | 57.5% | -15.4% |
| 6 | P | Everpure | 55.1% | n/a |
| 7 | PTC | PTC | 50.3% | 11.2% |
| 8 | SECZ | Securitize | 50.2% | n/a |
| 9 | MRNA | Moderna | 45.3% | n/a |
| 10 | RXO | RXO | 44.4% | 128.9% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LQDA | Liquidia | -59.5% | -18.8% |
| 2 | KDK | Kodiak AI | -57.0% | -84.8% |
| 3 | QURE | uniQure | -51.0% | -5.8% |
| 4 | EMAT | Evolution Metals & Technologies | -46.9% | n/a |
| 5 | GLAS | Glass House Brands | -45.8% | n/a |
| 6 | NKTR | Nektar Therapeutics | -44.4% | -3.5% |
| 7 | AVBP | ArriVent BioPharma | -43.9% | -16.9% |
| 8 | XENE | Xenon Pharmaceuticals | -38.7% | -19.3% |
| 9 | SWRD | Stewards | -38.0% | -50.2% |
| 10 | PCT | PureCycle Technologies | -37.3% | -54.2% |
The Tape Rewards Attention. It Punishes Reaction
Big daily moves pull hard at both greed and fear, and acting on either, day after day, is how most portfolios end up trailing the index they were trying to beat.
The Trefis High Quality (HQ) Portfolio is built for the opposite reflex: about 30 quality businesses screened for the fundamentals that survive volatile stretches, held with rules instead of reactions. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Read the movers daily; trade them rarely.