Market Movers | Winners: PENG, AVBP, PRME | Losers: HESM, ALMR, FCEL
On Wednesday, October 7, the S&P 500 slipped 0.2%, the Nasdaq-100 edged down 0.2% and the Dow Jones Industrial Average declined 0.7%. The S&P 500 is now up 2.0% over five trading days and up 1.7% over the past month.
Decliners outnumbered gainers 2,973 to 1,124 within the Trefis coverage universe. Penguin Solutions (PENG) gained 13.1% to lead the day, while Hess Midstream (HESM) fell 14.6%, the weakest showing.
Wednesday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the highest returns on Wednesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PENG | Penguin Solutions | 13.1% | 271.2% |
| 2 | AVBP | ArriVent BioPharma | 11.9% | -16.1% |
| 3 | PRME | Prime Medicine | 11.4% | 12.4% |
| 4 | VALU | Value Line | 8.4% | 18.9% |
| 5 | BRZE | Braze | 8.0% | -17.0% |
| 6 | EVH | Evolent Health | 7.8% | 3.5% |
| 7 | DRUG | Bright Minds Biosciences | 7.8% | -33.4% |
| 8 | PSIX | Power Solutions International | 7.7% | -9.6% |
| 9 | BKV | BKV | 7.4% | -12.8% |
| 10 | NWE | NorthWestern Energy | 7.3% | 18.0% |
Wednesday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the lowest returns on Wednesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | HESM | Hess Midstream | -14.6% | 1.8% |
| 2 | ALMR | Alamar Biosciences | -13.9% | n/a |
| 3 | FCEL | FuelCell Energy | -11.1% | 151.2% |
| 4 | SECZ | Securitize | -10.2% | n/a |
| 5 | ABSI | Absci | -10.2% | 164.2% |
| 6 | IESC | IES | -9.7% | n/a |
| 7 | FSM | Fortuna Mining | -9.5% | 3.2% |
| 8 | OPTX | Syntec Optics | -9.5% | 210.8% |
| 9 | CDNL | Cardinal Infrastructure | -9.2% | 7.8% |
| 10 | FWDI | Forward Industries | -9.2% | 11.8% |
Few Of Wednesday’s Biggest Movers Were Already Running
No stock on Wednesday’s one-day lists appears on the same side of the one-month lists, so the day’s biggest moves were fresh ones rather than extensions of a monthly trend.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | RXO | RXO | 38.6% | 124.4% |
| 2 | PTC | PTC | 38.0% | 11.1% |
| 3 | OPCH | Option Care Health | 37.9% | -2.7% |
| 4 | PENG | Penguin Solutions | 32.8% | 271.2% |
| 5 | MAT | Mattel | 29.3% | -17.5% |
| 6 | PRME | Prime Medicine | 27.7% | 12.4% |
| 7 | CCOI | Cogent Communications | 27.6% | -53.7% |
| 8 | CIEN | Ciena | 26.9% | 90.9% |
| 9 | HTZ | Hertz Global | 24.0% | -59.7% |
| 10 | AAOI | Applied Optoelectronics | 23.5% | 251.5% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AVBP | ArriVent BioPharma | -44.2% | -16.1% |
| 2 | ACRS | Aclaris Therapeutics | -35.4% | 13.0% |
| 3 | NKTR | Nektar Therapeutics | -33.5% | -4.8% |
| 4 | EMAT | Evolution Metals & Technologies | -31.4% | n/a |
| 5 | AGEN | Agenus | -23.8% | 141.1% |
| 6 | SECZ | Securitize | -21.9% | n/a |
| 7 | SPHR | Sphere Entertainment | -21.0% | 11.7% |
| 8 | IART | Integra Lifesciences | -20.1% | 4.7% |
| 9 | TWST | Twist Bioscience | -19.5% | 390.7% |
| 10 | ALMR | Alamar Biosciences | -18.5% | n/a |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PACB | Pacific Biosciences of California | 106.1% | 45.5% |
| 2 | GRAL | GRAIL | 68.0% | n/a |
| 3 | DNA | Ginkgo Bioworks | 65.3% | 38.0% |
| 4 | MXL | MaxLinear | 61.4% | 515.9% |
| 5 | BALY | Ballys | 53.6% | -16.3% |
| 6 | P | Everpure | 50.9% | n/a |
| 7 | ACVA | ACV Auctions | 48.5% | 30.2% |
| 8 | IOVA | Iovance Biotherapeutics | 48.4% | 373.1% |
| 9 | SVIA | Silvia | 46.5% | n/a |
| 10 | VICR | Vicor | 46.3% | 158.0% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LQDA | Liquidia | -60.6% | -22.6% |
| 2 | KDK | Kodiak AI | -56.3% | -84.4% |
| 3 | QURE | uniQure | -49.3% | -3.3% |
| 4 | NKTR | Nektar Therapeutics | -46.6% | -4.8% |
| 5 | EMAT | Evolution Metals & Technologies | -45.1% | n/a |
| 6 | AVBP | ArriVent BioPharma | -44.2% | -16.1% |
| 7 | ACRS | Aclaris Therapeutics | -43.9% | 13.0% |
| 8 | PCT | PureCycle Technologies | -41.6% | -55.8% |
| 9 | XENE | Xenon Pharmaceuticals | -38.9% | -18.8% |
| 10 | GLAS | Glass House Brands | -38.6% | n/a |
Today’s Winner Is Tomorrow’s Loser Often Enough
The movers list is the most honest picture of single-stock risk the market prints each day: the same volatility that makes the winners column also fills the losers column, and no one reliably knows which side a stock lands on next.
That is the case for owning a disciplined basket instead of chasing the tape. The Trefis High Quality (HQ) Portfolio holds roughly 30 businesses selected for consistent cash generation, strong margins, and resilient balance sheets, sized and rebalanced with rules. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Watch the movers for information; let the portfolio do the compounding.