Market Movers | Winners: OPCH, STDN, HTZ | Losers: AVBP, TWST, TXG
The S&P 500 advanced 0.6% on Tuesday, October 6, while the Nasdaq-100 gained 0.5% and the Dow Jones Industrial Average rose 0.5%. The S&P 500 is now up 1.9% over five trading days and up 1.3% over the past month.
Within the Trefis coverage universe, 2,003 stocks rose and 2,064 fell. The day’s best return belonged to Option Care Health (OPCH) (+32.6%) and the worst to ArriVent BioPharma (AVBP) (-47.0%).
Tuesday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the highest returns on Tuesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | OPCH | Option Care Health | 32.6% | -2.7% |
| 2 | STDN | Standard Nuclear | 16.8% | n/a |
| 3 | HTZ | Hertz Global | 15.1% | -59.9% |
| 4 | FCEL | FuelCell Energy | 14.3% | 182.5% |
| 5 | CIEN | Ciena | 13.8% | 89.7% |
| 6 | SWRD | Stewards | 13.2% | -48.0% |
| 7 | TLN | Talen Energy | 12.4% | -0.5% |
| 8 | CEG | Constellation Energy | 12.2% | -14.6% |
| 9 | APOG | Apogee Enterprises | 12.2% | 12.3% |
| 10 | LVWR | LiveWire | 10.9% | -63.1% |
Tuesday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the lowest returns on Tuesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AVBP | ArriVent BioPharma | -47.0% | -25.0% |
| 2 | TWST | Twist Bioscience | -18.6% | 426.4% |
| 3 | TXG | 10x Genomics | -17.5% | 394.5% |
| 4 | DNA | Ginkgo Bioworks | -17.2% | 49.3% |
| 5 | ALMR | Alamar Biosciences | -15.4% | n/a |
| 6 | APMD | Apnimed | -14.3% | n/a |
| 7 | AGEN | Agenus | -14.2% | 138.5% |
| 8 | TEM | Tempus AI | -13.8% | 21.9% |
| 9 | SYRE | Spyre Therapeutics | -13.6% | 144.5% |
| 10 | ACRS | Aclaris Therapeutics | -13.3% | 22.9% |
Some Of Tuesday’s Biggest Moves Were Weeks In The Making
ArriVent BioPharma (AVBP) appears on both the one-day and one-month losers lists. It fell 47.0% on Tuesday and is down 51.2% over the past month; excluding Tuesday, it had already lost 8.0% over the other sessions.
Aclaris Therapeutics (ACRS) added to a longer slide: after Tuesday’s 13.3% decline, the stock is down 40.0% over the past month, and it was already down 30.8% before Tuesday.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PACB | Pacific Biosciences of California | 47.5% | 44.4% |
| 2 | PTC | PTC | 40.3% | 10.8% |
| 3 | RXO | RXO | 37.8% | 125.8% |
| 4 | OPCH | Option Care Health | 35.9% | -2.7% |
| 5 | OPTX | Syntec Optics | 32.5% | 243.4% |
| 6 | AAOI | Applied Optoelectronics | 29.3% | 273.4% |
| 7 | CCOI | Cogent Communications | 26.8% | -56.6% |
| 8 | STDN | Standard Nuclear | 26.4% | n/a |
| 9 | CIEN | Ciena | 25.0% | 89.7% |
| 10 | MTSI | MACOM Technology Solutions | 23.4% | 104.7% |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LQDA | Liquidia | -63.3% | -24.9% |
| 2 | AVBP | ArriVent BioPharma | -48.9% | -25.0% |
| 3 | EMAT | Evolution Metals & Technologies | -34.0% | n/a |
| 4 | NKTR | Nektar Therapeutics | -32.6% | -5.6% |
| 5 | ACRS | Aclaris Therapeutics | -29.9% | 22.9% |
| 6 | AGEN | Agenus | -24.3% | 138.5% |
| 7 | GLAS | Glass House Brands | -24.0% | n/a |
| 8 | APMD | Apnimed | -22.0% | n/a |
| 9 | SPHR | Sphere Entertainment | -21.5% | 10.8% |
| 10 | IART | Integra Lifesciences | -20.0% | 7.2% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | INDP | Indaptus Therapeutics | 112.3% | -11.0% |
| 2 | PACB | Pacific Biosciences of California | 100.0% | 44.4% |
| 3 | DNA | Ginkgo Bioworks | 78.6% | 49.3% |
| 4 | MXL | MaxLinear | 74.2% | 527.1% |
| 5 | SECZ | Securitize | 71.2% | n/a |
| 6 | GRAL | GRAIL | 70.9% | n/a |
| 7 | BNC | BNB Standard | 67.6% | -8.9% |
| 8 | VICR | Vicor | 58.7% | 173.1% |
| 9 | SVIA | Silvia | 57.1% | n/a |
| 10 | BALY | Ballys | 53.2% | -15.3% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LQDA | Liquidia | -62.3% | -24.9% |
| 2 | KDK | Kodiak AI | -55.0% | -84.2% |
| 3 | AVBP | ArriVent BioPharma | -51.2% | -25.0% |
| 4 | QURE | uniQure | -48.2% | -3.6% |
| 5 | NKTR | Nektar Therapeutics | -46.2% | -5.6% |
| 6 | GLAS | Glass House Brands | -41.9% | n/a |
| 7 | CABA | Cabaletta Bio | -41.8% | -7.8% |
| 8 | ACRS | Aclaris Therapeutics | -40.0% | 22.9% |
| 9 | ASMB | Assembly Biosciences | -39.4% | -34.8% |
| 10 | XENE | Xenon Pharmaceuticals | -38.8% | -18.4% |
The Tape Rewards Attention. It Punishes Reaction
Big daily moves pull hard at both greed and fear, and acting on either, day after day, is how most portfolios end up trailing the index they were trying to beat.
The Trefis High Quality (HQ) Portfolio is built for the opposite reflex: about 30 quality businesses screened for the fundamentals that survive volatile stretches, held with rules instead of reactions. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Read the movers daily; trade them rarely.