Market Movers | Winners: PACB, MNKD, CTNM | Losers: LQDA, GLAS, QNC
On Wednesday, September 30, the S&P 500 declined 0.3%, the Nasdaq-100 edged up 0.2% and the Dow Jones Industrial Average slipped 0.9%. Over the past week the S&P 500 is down 0.7%, and over the past month it is down 0.5%.
Within the Trefis coverage universe, 1,373 stocks rose and 2,712 fell. Pacific Biosciences of California (PACB) gained 29.5% to lead the day, while Liquidia (LQDA) fell 57.2%, the weakest showing.
Wednesday’s Market Winners
The 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the highest returns on Wednesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PACB | Pacific Biosciences of California | 29.5% | 26.7% |
| 2 | MNKD | MannKind | 16.8% | -31.2% |
| 3 | CTNM | Contineum Therapeutics | 16.7% | 17.4% |
| 4 | UTHR | United Therapeutics | 12.5% | 11.2% |
| 5 | CDNL | Cardinal Infrastructure | 11.8% | 26.6% |
| 6 | OPTX | Syntec Optics | 11.3% | 188.5% |
| 7 | ROG | Rogers | 10.7% | 67.1% |
| 8 | CAPR | Capricor Therapeutics | 10.5% | n/a |
| 9 | CBNK | Capital Bancorp | 10.3% | 41.1% |
| 10 | FORM | FormFactor | 9.6% | 167.7% |
Wednesday’s Market Losers
And the 10 US-listed stocks in the Trefis coverage universe worth at least $300 million with the lowest returns on Wednesday:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LQDA | Liquidia | -57.2% | -12.3% |
| 2 | GLAS | Glass House Brands | -17.4% | n/a |
| 3 | QNC | Quantum eMotion | -15.4% | n/a |
| 4 | ETON | Eton Pharmaceuticals | -13.0% | 204.5% |
| 5 | BXBL | BOXABL | -12.6% | n/a |
| 6 | STC | Stewart Information Services | -12.4% | -27.5% |
| 7 | EMAT | Evolution Metals & Technologies | -12.4% | n/a |
| 8 | TRLV | Trulieve Cannabis | -12.2% | n/a |
| 9 | ADV | Advantage Solutions | -12.1% | n/a |
| 10 | JBL | Jabil | -10.0% | 25.9% |
For A Few Names, Wednesday Extended A Monthly Trend
The 29.5% gain in Pacific Biosciences of California (PACB) on Wednesday was not a one-off: the stock is up 74.9% over the past month, and up 35.1% over the sessions before Wednesday.
Liquidia (LQDA) is also on the one-month losers list (down 55.6%), but that move came almost entirely from Wednesday: over the rest of the month the stock was up 3.7%.
Movers Over The Last Week
Widening the window to five trading days, these are the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | PACB | Pacific Biosciences of California | 68.1% | 26.7% |
| 2 | DNA | Ginkgo Bioworks | 49.5% | 54.4% |
| 3 | IOVA | Iovance Biotherapeutics | 45.4% | 442.9% |
| 4 | FBYD | Falcons Beyond Global | 26.5% | -43.7% |
| 5 | TWST | Twist Bioscience | 21.9% | 509.2% |
| 6 | PWP | Perella Weinberg Partners | 21.8% | -4.6% |
| 7 | MNTK | Montauk Renewables | 20.0% | 63.5% |
| 8 | CDNA | CareDx | 19.7% | 245.0% |
| 9 | TXG | 10x Genomics | 19.5% | 454.0% |
| 10 | P | Everpure | 19.3% | n/a |
Losers
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | LQDA | Liquidia | -55.2% | -12.3% |
| 2 | QURE | uniQure | -43.5% | 1.0% |
| 3 | KDK | Kodiak AI | -35.4% | -82.4% |
| 4 | FICO | Fair Isaac | -32.6% | -65.0% |
| 5 | GLAS | Glass House Brands | -28.5% | n/a |
| 6 | QNC | Quantum eMotion | -27.1% | n/a |
| 7 | EMAT | Evolution Metals & Technologies | -23.5% | n/a |
| 8 | OCUL | Ocular Therapeutix | -23.3% | -36.8% |
| 9 | ADV | Advantage Solutions | -22.6% | n/a |
| 10 | VKTX | Viking Therapeutics | -21.7% | -7.3% |
Movers Over The Last Month
And over the last 21 trading days, the strongest and weakest names in the Trefis coverage universe:
Winners
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | SECZ | Securitize | 125.9% | n/a |
| 2 | BNC | CEA Industries | 90.6% | -8.3% |
| 3 | DNA | Ginkgo Bioworks | 88.4% | 54.4% |
| 4 | IOVA | Iovance Biotherapeutics | 81.4% | 442.9% |
| 5 | SVIA | Silvia | 79.4% | n/a |
| 6 | PACB | Pacific Biosciences of California | 74.9% | 26.7% |
| 7 | SDGR | Schrodinger | 59.2% | 73.7% |
| 8 | MNTK | Montauk Renewables | 58.7% | 63.5% |
| 9 | VICR | Vicor | 54.0% | 163.6% |
| 10 | BALY | Ballys | 53.1% | -16.9% |
Losers
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ALMS | Alumis | -66.1% | -24.3% |
| 2 | LQDA | Liquidia | -55.6% | -12.3% |
| 3 | QURE | uniQure | -50.4% | 1.0% |
| 4 | KDK | Kodiak AI | -49.2% | -82.4% |
| 5 | FICO | Fair Isaac | -48.4% | -65.0% |
| 6 | CTEV | Claritev | -46.8% | -50.5% |
| 7 | METC | Ramaco Resources | -41.9% | -54.1% |
| 8 | RARE | Ultragenyx Pharmaceutical | -40.4% | -34.7% |
| 9 | CXM | Sprinklr | -39.7% | -36.4% |
| 10 | ALHC | Alignment Healthcare | -39.1% | -58.7% |
The Tape Rewards Attention. It Punishes Reaction
Big daily moves pull hard at both greed and fear, and acting on either, day after day, is how most portfolios end up trailing the index they were trying to beat.
The Trefis High Quality (HQ) Portfolio is built for the opposite reflex: about 30 quality businesses screened for the fundamentals that survive volatile stretches, held with rules instead of reactions. It has a track record of outpacing a benchmark that combines the S&P 500, the S&P MidCap 400, and the Russell 2000. Read the movers daily; trade them rarely.