Merck’s Q3 Earning Review: Keytruda, The Key To Merck’s Growth

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Merck (NYSE: MRK) reported its Q3’16 earnings on October 26th. The company posted revenue growth of 6% (excluding currency effects) for the last quarter on year-over-year basis. Keytruda, is turning out to be a winner in oncology space and we expect it to be strong growth driver going forward. We also expect growth for Zepatier over the coming period. We expect it to generate about $1 billion in revenue in couple of years. The company has recently lost exclusivity in some of its important drugs. These will drag the revenue growth. Overall, we expect growth in low single digit for the next couple of quarters on a year-over-year basis. Over the last 9-months Merck has generated about $29.7 billion in sales and appears to be in line with achieving its guidance of $39.7 to $40.2 billion. The company posted non-GAAP EPS of $1.07 for Q3’16 up about 11% from $0.96 in same period last year on account of higher sales and reduced marketing expense as percentage of sales.

Our price estimate of $63 per share for Merck is under update

Keytruda – Strongest Arm In Arsenal

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Keytruda is turning up as a blockbuster drug for Merck. Year-to-date it has generated over $900 million in sales. Listed below are the areas where the drug has FDA approval:

  1. Melanoma
  2. Second Line Lung Cancer
  3. First Line with metastatic non-small cell lung cancer (NSCLC) with PD-L1 > 50%
  4. Bladder Cancer
  5. Head & Neck Cancer

With the recent approval, for treatment of first line NSCLC with PD-L1 > 50%, Keytruda should be able to tap large patient pool as it is the only drug in this category right now. Further, after the recent debacle of Bristol-Myers Opdivo, Keytruda has additional tailwind.  We expect the drug to add over $4 billion in revenue by 2020.

Challenges On Other Fronts To Drag Revenue Growth

The company lost exclusivity for Cubicin and is now faced with competition from generics. Going forward we expect this billion dollar drug to significantly lose market share. There are also impending expiry for Zetia and Vytrion in the next year. These will drag revenue going forward.

Further, Gardasil, a $2 billion drug, is also faced with challenges as the practitioners will move from three doses to two doses. The company recently increased prices which will counterbalance the volume decline. However, we expect the sales growth to be hit in fiscal 2017.

Januvia is an important drug with close to $4 billion in annual revenue. Here the company is faced with pricing pressure and competition. Despite this we believe large pool of diabetes patients will keep on driving TRx volume and help it maintain sales at close to the present level in near future.

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