AMGN’s One-Day Drop Offers a Chance to Reevaluate UTHR

AMGN: Amgen logo
AMGN
Amgen

United Therapeutics (UTHR) offers superior revenue growth across key periods, better profitability, and relatively lower valuation vs Amgen (AMGN), suggesting you may be better off investing in UTHR

  • UTHR’s quarterly revenue growth was 11.7%, vs. AMGN’s 9.4%.
  • In addition, its Last 12 Months revenue growth came in at 17.6%, ahead of AMGN’s 15.6%.
  • UTHR leads on profitability over both periods – LTM margin of 50.1% and 3-year average of 50.0%.

AMGN develops and delivers human therapeutics targeting inflammation, oncology, bone health, cardiovascular, nephrology, and neuroscience, including treatments for psoriasis, arthritis, and cardiovascular risk reduction. UTHR develops and commercializes therapies for chronic, life-threatening diseases, focusing on pulmonary arterial hypertension and related conditions to improve patient exercise capacity and symptoms.

Valuation & Performance Overview

  AMGN UTHR Preferred
     
Valuation      
P/EBIT Ratio 20.6 8.9 UTHR
     
Revenue Growth      
Last Quarter 9.4% 11.7% UTHR
Last 12 Months 15.6% 17.6% UTHR
Last 3 Year Average 9.3% 19.9% UTHR
     
Operating Margins      
Last 12 Months 21.8% 50.1% UTHR
Last 3 Year Average 26.6% 50.0% UTHR
     
Momentum      
Last 3 Year Return 27.2% 36.4% UTHR

Note: For “Last 3 Year Return” metric, preferred stock is one with higher returns unless the returns are too high (>300%) which creates risk of sell off.
See more revenue details: AMGN Revenue Comparison | UTHR Revenue Comparison
See more margin details: AMGN Operating Income Comparison | UTHR Operating Income Comparison
 
But do these numbers tell the full story? Read Buy or Sell UTHR Stock to see if United Therapeutics’s edge holds up under the hood or if Amgen still has cards to play (see Buy or Sell AMGN Stock).

Relevant Articles
  1. Triggers That Could Ignite the Next Rally In Rivian Automotive Stock
  2. What Could Spark the Rivian Automotive Stock’s Next Big Move
  3. 3 Forces That Could Shake Oklo Stock
  4. Oklo Stock on the Edge: 3 Threats You Need to Know
  5. Oklo Stock Can Sink, Here Is How
  6. Cash Rich, Low Price – Remitly Global Stock to Break Out?

That is one way to look at stocks. Trefis High Quality Portfolio evaluates much more, and is designed to reduce stock-specific risk while giving upside exposure

Historical Market Performance

  2020 2021 2022 2023 2024 2025 Total [1] Avg Best
Returns
AMGN Return -2% 2% 20% 13% -7% 11% 47%  
UTHR Return 72% 42% 29% -21% 60% -14% 234% <===
S&P 500 Return 16% 27% -19% 24% 23% 8% 93%  
Monthly Win Rates [3]
AMGN Win Rate 67% 33% 58% 58% 50% 57%   54%  
UTHR Win Rate 58% 67% 42% 42% 58% 14%   47%  
S&P 500 Win Rate 58% 75% 42% 67% 75% 57%   62% <===
Max Drawdowns [4]
AMGN Max Drawdown -24% -10% -2% -17% -8% -1%   -10% <===
UTHR Max Drawdown -10% 0% -23% -26% -4% -22%   -14%  
S&P 500 Max Drawdown -31% -1% -25% -1% -2% -15%   -12%  

[1] Cumulative total returns since the beginning of 2020
[2] 2025 data is for the year till date (YTD)
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year

 
No matter how good the numbers, stock investment is never a smooth ride. There is a risk you must factor in. Read UTHR Dip Buyer Analyses to see how the stock has fallen and recovered in the past.