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Investment Overview for Johnson & Johnson (NYSE:JNJ)
Below are key factors that present opportunities for upside or downside to the current Trefis price estimate for J&J:
Immunology and Oncology pipeline firing
- J&J's Revenue from Remicade and Immunology Drugs and J&J's Other Pharmaceuticals Revenue: Despite the fall of J&J's hepatitis C drug Olysio, there still exists some potential in its pharma business that can be unlocked. Its immunology and oncology drugs can do well assuming Remicade holds on to its position in the U.S. where it still has some protection from biosimilar competition. Other immunology drugs such as Simponi and Stelara are growing fast. J&J’s oncology division, although small, is doing well. The addition of Imbruvica is likely to help. We have factored in these expectations in our price estimate. However, positive data pipeline drug trials could lead to our forecasts being conservative. For instance, there are additional clinical data that could potentially strengthen Imbruvica's sales going forward. Also, the company is likely to file multiple immunology and oncology drugs for FDA review in the next two to three years. More than expected success could add additional $5-$6 billion in annual revenues by 2021. This could lead to an upswing of about 10% in J&J's stock price.
Medical devices business crumbles under competitive pressure
- J&J's Share in Spinal and Orthopedics Devices Market and J&J's Surgical Devices Revenue: The revenues from J&J's medical devices & diagnostics segment declined by more than 3% in 2014 which can be partially attributed to divestiture and partially to competitive pressure, which has resulted in lower prices. J&J is a world leader in medical devices and diagnostics, and its acquisition of Synthes has stengthened its orthopaedics portfolio. Despite its strong market position, the segment's growth has flattened out, which has led to trimming of the business through divestitures such as Ortho-Clinical Diagnostics and Cordis. Competition from lesser known names has led to pricing pressure, which has brought down incremental growth despite increased shipments. We currently expect low growth in medical devices and diagnostics business. However, if the competition intensifies and J&J fails to find new growth drivers, its revenues can dip further by $5-$6 billion leading to approximately 10% downside.
Johnson & Johnson (NYSE:JNJ) is an American multinational pharmaceutical, medical devices and consumer packaged goods manufacturer founded in 1886. The company (also called J&J) and its subsidiaries are engaged in the research and development, manufacture and sale of a range of products in the health care field. It has more than 250 operating companies conducting business worldwide.
J&J is an industry bellwether and therefore its shares generally reflect the overall performance in healthcare products at any given point in time. It also reflects investor appeal for “defensive” securities, as during periods of economic or market uncertainty investors have generally sought haven in J&J shares as its earnings are less cyclical.
Some of its iconic brands include Band-Aid, Listerine, Neutrogena, Tylenol, Zyrtec, Remicade, Rieperdal and Topamax among many others. The company has sold ortho-clinical diagnostics to Carlyle group.
We believe that both pharmaceuticals and medical devices business are almost equally important to J&J's value.
Pharmaceuticals business has grown significantly in the past few years
J&J's pharmaceutical business accounted for nearly 45% of its revenues in 2014 and more than 50% of EBITDA (earnings before interest, taxes, depreciation and amortization). These percentages have increased over the last few years, thanks to the growth in immunology and oncology drugs. Besides, the division has significantly higher EBITDA margin (~ 55%) as compared to consumer business, and slightly higher than that of medical devices segment.
Strong market position in medical devices industry
J&J has leading market position in several sub-segments of the medical devices market due to its diversified product offerings, established brand, R&D focus, and strong sales and marketing capabilities. Medical devices business constituted roughly 35% of total revenues in 2014 and nearly 40% of EBITDA. Furthermore, J&J acquired Synthes in 2012, which is a global manufacturer of medical devices for orthopedics market including trauma and spine. The combined DePuy/Synthes orthopedic division has the broadest orthopedic portfolio globally and will help J&J expand its leadership.
Pharmaceutical business becoming increasingly important
J&J has made some great strides in the pharmaceutical sector in the last few years. The company, traditionally known for medical devices and diagnostics, is now becoming more centered around pharmaceutical business. The segment is witnessing strong growth driven by increasing sales of Remicade, Zytiga, Simponi and Stelara and Invega Sustena. In 2014, J&J announced the acquisition of biotech firm Alios BioPharma to leverage its potent drug pipeline catering to treatment of viral diseases.
Licensing and co-development arrangements
J&J has licensing/co-development/marketing
agreements with Bayer for Xarelto (Rivaroxaban), Elan for Bapineuzumab, Vertex for Telaprevir, and Millennium Pharmaceuticals for Velcade. J&J also acquired Cougar Biotech and Crucell to build out its oncology and vaccines businesses.
Loss of patents impacting sales
Over the last few years, several of J&J's drugs including Levaquin, Concerta, Invega & Aciphex lost their patent protection. Over the next few years, about 3-4 important drugs are expected to lose their patent and J&J will need to develop new drugs to offset these losses.
Growing threat of generic products
The fast growing pharma market in emerging economies or referred to as the 'Pharmerging' economies have the capability and technical prowess to manufacture generic versions of blockbuster drugs. These generic drugs are often sold at prices that substantially cheaper then their branded counterparts, thereby severely affecting big pharma's ability to generate profits in the long run. Remicade faces potential threat from biosimilars, which are generic versions of biologics. The drug is already witnessing significant sales decline in Europe where its biosimilar versions have been approved. However, J&J holds marketing rights for Americas, Japan and other regions. If a biosimilar version of Remicade is approved in the U.S., Remicade's sales, attributable to J&J, will suffer.
Globalization of healthcare reforms
Governments around the world are trying to rein in fiscal spending in order to manage their budget deficits
Since healthcare costs are one of the biggest components of any national budget, increased healthcare legislation and reforms around the world will hurt revenues for the entire pharmaceutical sector.
Trefis Forecast Rationale for J&J's Market Share of Vision Care, Diabetes and Other Medical Devices
Market share is defined as the global revenue generated by J&J's vision care, Cordis, diabetes care and ortho-clinical diagnostics units divided by the global revenue generated in these categories by medical device makers all over the world.
J&J had a market share of just above 5% in 2007, which drifted downwards by about 50 basis points in 2011, mainly due to spin-offs by J&J for the biopsy business and more recently, the coronary stents business.
We expect J&J to maintain its current market share within the segment by the end of the Trefis forecast period in 2018.
Trefis considered the following factors for its forecast:
- Acquisitions to bolster market share
- Medical devices business at J&J has seen both organic growth due to new product introductions and in-organic growth fueled by acquisitions.
- Some major acquisitions in the past have included Cordis in 1996 for $1.8 billion, Conor Medsystems in 2007 for $1.4 billion, and the Inverness diabetes business in 2001 for $1.3 billion.
- Deals like Synthes and other potential acquisitions will help in increasing market share over the future.
- Growth prospects for Cordis
- J&J's subsidiary, Biosense Webster is the leader in electro-physiology and cardiac ablation, offering
radio-frequency ablation catheters, diagnostic and mapping catheters, as well as advanced mapping, navigation and visualization systems. Biosense Webster sales have generally grown in the double digits over the last 2-3 years.
- Atrial fibrillation increases significantly with age and an estimated 4-5 million Americans suffer from it annually.
- J&J has state of the art products in this segment like the Thermocool ablation catheter system, which is approved for the treatment of patients with Type I atrial flutter and patients with drug refractory ventricular tachycardia.
- Exciting products in the pipeline include the next generation Thermocool ablation catheter and next generation CARTO 3 V2 cardiac navigation and mapping system.
- Market share gains in diabetes care
- Continuous glucose monitoring(CGM) devices allow for the real time monitoring of blood glucose levels as opposed to the intermittent testing performed in blood glucose meters.
- Wireless integration between an insulin pump and CGM provides the groundwork for what could ultimately result in a closed loop diabetes management system.
- In June, J&J received CE Mark (abbreviation of French: Conformité Européenne, meaning "European Conformity", formerly EC mark) for its Animas Vibe CGM-enabled insulin pump. The Vibe is J&J’s first device to offer integrated pump and continuous glucose monitoring (CGM), which should help J&J’s share versus that of Medtronic Minimed. J&J plans to submit the PMA (Pre-Market Approval) filing in the US for Animas Vibe this year.
- Clear vision in eye care
- J&J vision care division develops and markets the Acuvue brand of contact lenses, including the 1-day Acuvue TruEye, 1-day Acuvue for astigmatism, Acuvue Oasys with Hydraclear Plus, and the 1-day Acuvue Moist.
- J&J sees growth in its vision care platform through penetration in emerging markets, geographic expansion, penetration of specialty lenses and a general
increase in the world population.
- Good diagnoses for diagnostic pipeline
- For 2012 and thereafter, the company plans to focus on developing reagent tests in the molecular and advanced cellular diagnostics segments, a new Cellex system for Crohn’s disease and a new circulating tumor cell platform (Veridex).
- In the longer term, J&J is working to develop personalized medicines and will try to leverage its broader scale to provide companion diagnostics for its pharmaceutical business, with a particular focus on earlier detection of chronic diseases.
Back to Company Overview
- Divestitures reduce market share
- J&J has pruned a number of businesses in MD&D such as the Advanced Wound Care and Biopsy businesses and more notably its recent decision to exit out of coronary stents,
which was driven by the market environment and company specific issues.
- MD&D’s year-over-year sales growth rate has significantly slowed in the past five years in large part due to the decline in the drug eluting stent business as well as the overall effects of the economy and change in the pricing environment.
- Obstacles in continuous glucose monitoring (CGM) market
- There are several obstacles which must be overcome before true closed loop diabetes management system can be developed.
- The first challenging task is to create an algorithm with a level of sophistication capable of treating a diverse patient pool, many of whom may react differently to insulin infusions.
- The timeliness of data has to be increased as current CGMs measure glucose levels subcutaneously, which can lag actual glucose levels in the bloodstream by up to 20 minutes. This becomes problematic during periods of rapidly change blood sugar levels.
- In January 2010, J&J and the Juvenile Diabetes Research Foundation (JDRF) announced a non-exclusive partnership to develop a true closed loop system, results of which have not been particularly exciting.
How Does Trefis Modelling Work?
How do we get the historical numbers for this chart?
Trefis has a team of in-house Analysts who gather historical data from company filings and other verifiable sources. When historicals are available, we explain how we got them at the bottom of the Trefis analysis section below.
Who came up with the Trefis forecast for future years?
The Trefis team of in-house Analysts considers a variety of factors when projecting any forecast. The rationale for our projections is explained in the Trefis analysis section below.
How does my dragging the trendline on the chart impact the stock price?
- We use forecasts for business drivers to calculate forecasted Revenues and Profits for each division of the company.
- We then use forecasted Profits in a Discounted Cash Flow (DCF) model to obtain the Price Estimate for the company.
See more on: DCF Methodology
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